The 90-day mortality in patients with TIMI 3 before PCI was identical in the facilitated and the primary PCI groups (14/353, 4.0% vs. The rate of TIMI 3 flow before PCI was higher in the facilitated PCI group than in the primary PCI group (43.9 vs. The incidence of cardiogenic shock (6.2, 5.5, and 3.6%) and 90-day mortality (6.1, 4.7, and 4.0%) were lowest in the group with TIMI 3 patency before PCI, respectively. Complete ST resolution was observed most often in the TIMI 3 flow group (47.5, 53.6, and 58.6%). 1d), the occurrence of TIMI minor bleeding (aHR. The rates of TIMI 3 flow after PCI were 84.6, 89.7, and 95.6%, respectively. In patients with pre-TIMI 2/3, although the occurrence of TIMI major bleeding was similar between the 3-mo and 12-mo DAPT groups (Table 2 and Fig. For this analysis, patients were divided into three groups according to the TIMI flow of the infarct vessel before PCI: TIMI 0/1, TIMI 2, and TIMI 3.įrom a total of 1617 patients, 861 had TIMI 0/1, 279 had TIMI 2, and 477 TIMI 3 flow. Patients with STEMI <6 hours enrolled in the ASSENT-4 PCI study were randomized to facilitated PCI with tenecteplase or primary PCI. The purpose of the present analysis was to investigate whether TIMI 3 flow obtained with fibrinolysis before PCI is associated with a clinical outcome comparable to that in patients with spontaneous TIMI 3 flow. Most likely these patients had spontaneous recanalization of the infarct vessel and might constitute a low-risk subgroup. Previous studies have shown a low mortality in patients with TIMI 3 flow before primary percutaneous coronary intervention (PCI). Grade 2 (Partial perfusion): The contrast material passes. Grade 1 (Penetration without perfusion): The contrast material passes beyond the area of obstruction but hangs up and fails to opacify the entire coronary bed distal to the obstruction. Early restoration of blood flow of the infarct-related artery is associated with an improved outcome in patients with ST-elevation myocardial infarction (STEMI). Grade 0 (No perfusion): There is no antegrade flow beyond the point of occlusion.

Exertion timi flow 3